Aerosol deposition in the human upper airways

Application Challenge AC7-01 © copyright ERCOFTAC 2019

Test Data

Overview of tests

Major portions of this section were adopted from Lizal et al. (2015). The positron emission tomography (PET) method provides the best spatial resolution (among radiological methods). In addition to local deposition in the various sections, the deposition hot spots can also be evaluated. However, in comparison to the PET methodology, which is routinely applied to clinical examination, using this method in the in vitro design requires major modiﬁcations both in the aerosol preparation and, in particular, in the experiment evalu— ation approach. The method, based on PET and fulﬁlling the above mentioned criteria, is presented in the following.

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