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{{ACHeader
|area=7
|number=01
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__TOC__
=Aerosol deposition in the human upper airways=
'''Application Challenge AC7-01'''   © copyright ERCOFTAC 2019
=Evaluation=
==Comparison of Test Data and CFD==
[[Evaluation_AC7-01#figure20|Figure 20]] shows the comparison between LES, RANS and ''in vitro'' deposition results.
The error bars attached to the ''in vitro'' results at 60 L/min
([[Evaluation_AC7-01#figure20|figure 20(d)]]) correspond to
the estimated experimental uncertainties as reported by the authors
([[Best_Practice_Advice_AC7-01#lizal2015|Lizal ''et al.'', 2015]]).
Overall deposition in the geometry as predicted with LES and RANS is in good agreement
with the measured data (see [[Evaluation_AC7-01#figure20|figure 20(a)]]).
Concerning deposition in the segments of the
geometry, numerical and experimental results are shown to be in reasonable agreement at
15 and 60 L/min, whereas deviations are found at 30 L/min. Possible reasons for the observed
discrepancies include experimental uncertainties at the inlet related to the velocity
profile and the particle distribution. The in vitm inlet conditions might deviate from the
velocity profiles and uniform particle distribution assumed in the CFD simulations due
to the effect of the devices located upstream of the mouth in the experimental apparatus
([[Best_Practice_Advice_AC7-01#lizal2015|Lizal ''et al.'', 2015]]).
 
 
<div id="figure20"></div>
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|align="center"|[[Image:AC7-01_fig20a.png|650px]]
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|align="center"|[[Image:AC7-01_fig20b.png|650px]]
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|align="center"|[[Image:AC7-01_fig20c.png|650px]]
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|align="center"|[[Image:AC7-01_fig20d.png|650px]]
|-
|align="center" width=650|'''Figure 20:''' Comparison of deposition between LES, RANS and ''in vitro'' data.
|}
<br/>
----
{{ACContribs
|authors=P. Koullapis<sup>a</sup>, F. Lizal<sup>b</sup>, J. Jedelsky<sup>b</sup>, L. Nicolaou<sup>c</sup>, K. Bauer<sup>d</sup>, O. Sgrott<sup>e</sup>, M. Jicha<sup>b</sup>, M. Sommerfeld<sup>e</sup>, S. C. Kassinos<sup>a</sup>
|organisation=<br><sup>a</sup>Department of Mechanical and Manufacturing Engineering, University of Cyprus, Nicosia, Cyprus<br><sup>b</sup>Faculty of Mechanical Engineering, Brno University of Technology, Brno, Czech Republic<br><sup>c</sup>Division of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, Baltimore, USA<br><sup>d</sup>Institute of Mechanics and Fluid Dynamics, TU Bergakademie Freiberg, Freiberg, Germany<br><sup>e</sup>Institute Process Engineering, Otto von Guericke University, Halle (Saale), Germany
}}
{{ACHeader
|area=7
|number=01
}}
 
 
© copyright ERCOFTAC 2019

Latest revision as of 08:41, 21 October 2019

Front Page

Description

Test Data

CFD Simulations

Evaluation

Best Practice Advice

Aerosol deposition in the human upper airways

Application Challenge AC7-01   © copyright ERCOFTAC 2019

Evaluation

Comparison of Test Data and CFD

Figure 20 shows the comparison between LES, RANS and in vitro deposition results. The error bars attached to the in vitro results at 60 L/min (figure 20(d)) correspond to the estimated experimental uncertainties as reported by the authors (Lizal et al., 2015). Overall deposition in the geometry as predicted with LES and RANS is in good agreement with the measured data (see figure 20(a)). Concerning deposition in the segments of the geometry, numerical and experimental results are shown to be in reasonable agreement at 15 and 60 L/min, whereas deviations are found at 30 L/min. Possible reasons for the observed discrepancies include experimental uncertainties at the inlet related to the velocity profile and the particle distribution. The in vitm inlet conditions might deviate from the velocity profiles and uniform particle distribution assumed in the CFD simulations due to the effect of the devices located upstream of the mouth in the experimental apparatus (Lizal et al., 2015).


AC7-01 fig20a.png
AC7-01 fig20b.png
AC7-01 fig20c.png
AC7-01 fig20d.png
Figure 20: Comparison of deposition between LES, RANS and in vitro data.




Contributed by: P. Koullapisa, F. Lizalb, J. Jedelskyb, L. Nicolaouc, K. Bauerd, O. Sgrotte, M. Jichab, M. Sommerfelde, S. C. Kassinosa — 
aDepartment of Mechanical and Manufacturing Engineering, University of Cyprus, Nicosia, Cyprus
bFaculty of Mechanical Engineering, Brno University of Technology, Brno, Czech Republic
cDivision of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, Baltimore, USA
dInstitute of Mechanics and Fluid Dynamics, TU Bergakademie Freiberg, Freiberg, Germany
eInstitute Process Engineering, Otto von Guericke University, Halle (Saale), Germany

Front Page

Description

Test Data

CFD Simulations

Evaluation

Best Practice Advice


© copyright ERCOFTAC 2019