AC7-03: Difference between revisions
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Heart failure is a cardiovascular disease, which affects millions of people worldwide. If the heart failure is to severe, a heart transplantation is the gold standard for treatment. Unfortunately, a significant shortage of donor hearts exists worldwide. A technical solution to overcome this gap between demand and availability are Ventricular Assist Devices (VADs). The VADs are mainly implanted within the body of the patients and assist the weak heart by creating the needed pressure to sufficiently supply the blood flow in the circulatory system. | Heart failure is a cardiovascular disease, which affects millions of people worldwide. If the heart failure is to severe, a heart transplantation is the gold standard for treatment. Unfortunately, a significant shortage of donor hearts exists worldwide. A technical solution to overcome this gap between demand and availability are Ventricular Assist Devices (VADs). The VADs are mainly implanted within the body of the patients and assist the weak heart by creating the needed pressure to sufficiently supply the blood flow in the circulatory system. | ||
The devices must be designed in such a way that the operating range maintain the blood flow. For this purpose, a defined pressure head <math> H </math> must be built up at a certain blood flow rate <math> Q </math>. Whether a VAD design meets these requirements can be checked by flow simulations in the pre-clinical evaluation | The devices must be designed in such a way that the operating range maintain the blood flow. For this purpose, a defined pressure head <math> H </math> must be built up at a certain blood flow rate <math> Q </math>. Whether a VAD design meets these fluid mechanical requirements can be checked by flow simulations in the pre-clinical evaluation. | ||
Furthermore, a VAD must be designed for highest hemocompatibility, which means that the blood components in the flow are not damaged due to non-physiological flow condition. This can be checked by analysing the fluid dynamical stresses by flow simulations and combine them with a numerical blood damage prediction model (hemodynamical parameters). | |||
The present ERCOFTAC KB Wiki entry analyse the turbulent flow field in a VAD by flow simulations. A highly flow-resolving LES is compared as a reference with a turbulence modeling URANS methods (standard procedure in industry for flow simulation in VADs) with respect to the computed fluid mechanical and hemodynamical parameters. | |||
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* was wird in dieser Wiki gemacht? | * was wird in dieser Wiki gemacht? | ||
* Evaluation der fluidmechanischen Parameter (Förderhöhe und Wirkungsgrad) | * Evaluation der fluidmechanischen Parameter (Förderhöhe und Wirkungsgrad) | ||
* insbesondere: Vergleich von hämodynamischen Parametern --> äquivalente Spannung und Blutschädigungsparameter | * insbesondere: Vergleich von hämodynamischen Parametern --> äquivalente Spannung und Blutschädigungsparameter | ||
Revision as of 12:09, 16 December 2021
Turbulent Blood Flow in a Ventricular Assist Device
Application Area 7: Biomedical Flows
Application Challenge AC7-03
Abstract
Heart failure is a cardiovascular disease, which affects millions of people worldwide. If the heart failure is to severe, a heart transplantation is the gold standard for treatment. Unfortunately, a significant shortage of donor hearts exists worldwide. A technical solution to overcome this gap between demand and availability are Ventricular Assist Devices (VADs). The VADs are mainly implanted within the body of the patients and assist the weak heart by creating the needed pressure to sufficiently supply the blood flow in the circulatory system.
The devices must be designed in such a way that the operating range maintain the blood flow. For this purpose, a defined pressure head must be built up at a certain blood flow rate . Whether a VAD design meets these fluid mechanical requirements can be checked by flow simulations in the pre-clinical evaluation.
Furthermore, a VAD must be designed for highest hemocompatibility, which means that the blood components in the flow are not damaged due to non-physiological flow condition. This can be checked by analysing the fluid dynamical stresses by flow simulations and combine them with a numerical blood damage prediction model (hemodynamical parameters).
The present ERCOFTAC KB Wiki entry analyse the turbulent flow field in a VAD by flow simulations. A highly flow-resolving LES is compared as a reference with a turbulence modeling URANS methods (standard procedure in industry for flow simulation in VADs) with respect to the computed fluid mechanical and hemodynamical parameters.
- was wird in dieser Wiki gemacht?
* Evaluation der fluidmechanischen Parameter (Förderhöhe und Wirkungsgrad) * insbesondere: Vergleich von hämodynamischen Parametern --> äquivalente Spannung und Blutschädigungsparameter * wichtig für Design und Optimierung dieser Systeme
- Wo bisher veröffentlicht?
Contributed by: Benjamin Torner — University of Rostock, Germany
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